The results of μCT analysis of the femurs revealed a higher bone mass in the cKD mice as compared to controls (MB1-Cre;EPO-Rwt/wt), as measured by both cortical and trabecular volumetric bone mineral density (vBMD, 505 [95%CI 495-516] vs 478 [95%CI 458-498] mgHA/cm3 and 52.2 [95%CI 42.1-62.3] vs 40.8 [34.9-46.7] mgHA/cm3, respectively, p < 0.05) (Figure 4B,C). Here, EPO is linked to chronic kidney disease.