Secondly, the variant (rs1800553) from UAE S014 was described by ClinVar as “age-related macular degeneration 2, susceptibility to retinal dystrophy, inborn genetic diseases, cone rod dystrophy 3, ABCA4 Related Disorders” and has a UAE allele frequency as high as 1.9% (see Supplementary Table S17). This evidence concerns the gene ABCA4 and age-related macular degeneration.