PPP1R3B and hepatocellular carcinoma: Notably, siRNA-15 is the siRNA located closest to the variant rs4841132 in exon 2 of LOC157273. We also tested plasmid-based overexpression of LOC157273 in human hepatocytes and hepatoma cells but did not find alteration in levels of PPP1R3B expression (Supplementary Text and Figure S6).