PPARA and viral pneumonia: PPAR-γ agonist thiazolidinediones (TZDs), like pioglitazone and rosiglitazone, have anti-inflammatory properties with potential for corrective effects on severe viral pneumonia. Nutritional ligands of PPAR-γ, such as lemongrass, pomegranate, and curcuma may be used in conjunction with PPAR pharmacological agents (89).