C1S and atherosclerosis: The proteins associated with atherosclerosis are: IGHA1, serum amyloid A1 (SAA), and four complement cascade proteins: complement factor B (CFAB), complement C2 (CO2), complement C3 (CO3), and complement C1s (C1S) – a subcomponent that is proposed to be considered as biomarkers of the cardiovascular risk (Gordon et al., 2018).