FOSL1 and Sepsis: By combining discovery-based RNA sequencing studies in a neonatal mouse model of sterile sepsis complemented by validation strategies using genetic manipulation in primary fetal human lung endothelial cell (EC) and an immortalized lung EC line we developed, we identify the transcription factor FOSL1 (FOS like 1, also known as FRA-1, FOS-related antigen 1), as a novel regulator of endotoxin-mediated dysangiogenesis in the developing lung.