Regarding the up-regulated lncRNAs, only a low number of them have been previously implicated in cancer, such as the up-regulated CASC15, LINC00662, LINC01272, LINC00857, LINC00092, LINC00673 and the down-regulated LINC00657, LINC01087 and LINC00993. The gene discussed is LINC00993; the disease is cancer.