In HR+HER2− breast cancer, the baseline NLR was significantly associated with DFS in univariable analysis (HR 2.444; 95% CIs 1.617–3.692; P < 0.001) and multivariable analysis (HR 2.323; 95% CIs 1.537–3.511; P < 0.001; Supplementary Table 3), but not with OS (Supplementary Table 3). The gene discussed is ERBB2; the disease is breast cancer.