PIK3CA and non-small cell lung carcinoma: RAD001 can significantly inhibit the mTORC1 pathway and enhance radiosensitivity of NSCLC cells with wild-type phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) and Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) by suppressing epithelial-mesenchymal transition27.