STAT1 and infection: We noted weaker slicing of the vsiRNA target by the pan-Ago IP from Stat1/2−/− mice than from Rag1−/− mice in response to NoVΔB2 infection (Fig. 6C, compare lanes 3 and 5), which appeared to correlate with the lower levels of vsiRNAs induced by NoVΔB2 in Stat1/2−/− mice than in Rag1−/− mice (Fig. 3A and 6A).