The association between T-tau and verbal episodic memory was similar to NFL within the whole cohort (r = − 0.28, p < 0.04, Fig. 5c) but did not reach significance within the CSF AD group (r = − 0.15, p = 0.45) when analyzed by CSF profile (Fig. 5d). The gene discussed is NEFL; the disease is Alzheimer disease.