Another study indirectly linked vitamin B3 to uterine tumors, where nicotinamide phosphoribosyltransferase (NAMPT), which catalyzes one of the steps in NAD synthesis, was involved in tumors originating from the myometrium, such as rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS) [80]. Here, NAMPT is linked to leiomyosarcoma.