Besides this, to expedite the elucidation of regulatory network involved in NSCLC, a 3-node miRNA FFL was generated, consisting of a miRNA (miR-20b-5p), a hub gene (CCNB1), and two transcription factors (HMGA2 and E2F7) (Figure 5). The gene discussed is E2F7; the disease is non-small cell lung carcinoma.