CNTN1 and neoplasm: Interestingly, in a study exploring the therapeutic efficacy of Ganoderma lucidum extract (GLE), a potentially effective tumor growth inhibitor, CNTN1 was identified to be a part of the hub mRNA down-expressed in GLE-treated Hepa1–6-bearing C57BL/6 mice, mediated by miRNA mmu-miR23a-5p [105].