In fact, the surprising motor and sensory functions’ recovery in BoNT/A-treated mice was accompanied by gene expression modulation involved in muscular atrophy, such as Myogenin or Atrogin-1 and MuRF1 (two muscle-specific E3 ubiquitin ligases) [30], which were increased transcriptionally in saline mice’s quadriceps muscle. Here, TRIM63 is linked to muscular atrophy.