LRRC4 and central nervous system cancer: Many studies have shown that miRNA-38147, miRNA-182, and miR-381 48 can bind to LRRC4 and inhibit its expression, promoting the progression of glioma [47,48], In addition, the decreased expression of LRRC4 was associated with the occurrence and development of hematological non-Hodgkin’s lymphoma [49] and solid tumors such as meningioma, pituitary tumor [50], and nasopharyngeal carcinoma [51].