The study of Song et al. confirmed that in gastric cancer, lncRNA-KRTAP5-AS1 and lncRNA-TUBB2A promote the high expression of Claudin-4, which is related to poor prognosis of gastric cancer through competitive binding miRNA-596 and miRNA-3620-3P, promoting the proliferation, invasion and metastasis of gastric cancer cells [30]. Here, CLDN4 is linked to gastric cancer.