LCN2 and B-cell chronic lymphocytic leukemia: Representative immunoblotting with an antibody that bound to both dimeric (45 kDa) and monomeric NGAL (25 kDa) revealed the presence of endogenous NGAL (mainly as a dimer: ≥80%) in serum samples from healthy controls and from patients with CLL (four untreated patients and one patient in remission) (Figure 1E).