Mucopolysaccharidosis type II (MPS II), or Hunter Syndrome, is an X-linked lysosomal storage disease caused by deficiency of iduronate 2-sulfatase (IDS), a lysosomal enzyme involved in the catabolism of the glycosaminoglycans (GAGs) heparan sulfate (HS) and dermatan sulfate (DS) [1]. Here, IDS is linked to mucopolysaccharidosis type 2.