To identify factors involved in coagulation that may contribute to COVID-19-related coagulopathy, we used genes associated with the GO term “blood coagulation” and the GTEx database resulting in four procoagulants, whose expression was higher in males than in females and increased with age (ADAMTS13, F11, HGFAC, KLKB1), and two anticoagulants, whose expression was higher in females and decreased with age (C1QTNF1, SERPINA5). This evidence concerns the gene KLKB1 and blood coagulation disease.