Moreover, the results in Figure 4 demonstrate that the expression of miR-182-5p is dependent on the PI3K/AKT signaling pathway in ZR75-1 cells (Figure 4C), suggesting that the expression of miR-182-5p may be correlated with PTEN and the AKT regulation in the luminal breast tumor cell lines. The gene discussed is PTEN; the disease is breast neoplasm.