ERBB2 and breast cancer: To substantiate further the applicability of EphB4 as target for breast cancer imaging, we have investigated the binding of the EphB4 polyclonal antibody used for IHC, which detects extracellular, domains, for flow cytometry on a panel of breast cancer cell lines selected for respectively low (MCF-10A), intermediate (MCF-7 and MDA-MB-231) and high (HCC1954) expression of Her2.