NLRP3 and atherosclerosis: Deletion or inhibition of the NLRP3 inflammasome complex, including NLRP3, ASC, or IL-1β, was shown to improve lipid metabolism, and to decrease inflammation, pyroptosis, and infiltration of more immune cells into plaques, thus ameliorating inflammatory responses and atherosclerosis progression [87,88,143,144,145,146,147,148,149,150,151].