In order to evaluate whether Fyn might be a valuable strategy to reduce pAPP-Tyr and prevent Aβ42 production in neurons, we selected neurons from five patients, four diagnosed with AD (patient no. 87F, 31F, 38F, and 53M) and one diagnosed with FTD (patient no. 64F) all provided by Axol Bioscience. This evidence concerns the gene FYN and Alzheimer disease.