The discovery and description of the crystal structure of the mutated BRAF protein [10] led to the development of several specific inhibitors, such as vemurafenib, dabrafenib, and encorafenib, which have been approved both in the US and Europe for the treatment of advanced (AJCC stage IIIC and stage IV) MM-harboring BRAF V600 mutations [11,12,13,14]. The gene discussed is BRAF; the disease is Miyoshi myopathy.