From a molecular mechanistic perspective, the expression of peroxisome proliferator activated receptor gamma (PPARγ), a key gene with anti-inflammatory (peripheral, intestinal and neuroinflammation) [58] and anti-dysbiotic effects [59] is considerably reduced in ulcerative colitis [60] and celiac disease [61,62,63] patients. The gene discussed is PPARG; the disease is ulcerative colitis.