IL1B and Psoriasiform dermatitis: The high-fat diet rich in SFAs exacerbates the IMQ-induced psoriasiform dermatitis in mice [13,14]; SFAs activate nucleotide-binding domain, leucine-rich repeats containing family, pyrin domain-containing-3 (NLRP3) inflammasome which generates active IL-1β and IL-18 in CD11c+ macrophages [14,15,16].