In particular, genetic alterations in the human TOR1AIP1 gene, which encodes lamina-associated polypeptide 1 (LAP1), have collectively been implicated in severe cases of cardiomyopathy, muscular dystrophy, dystonia and brain atrophy [9,10,11,12,13,14,15]. This evidence concerns the gene TOR1AIP1 and cardiomyopathy.