Results from both CTRP (Figure 3A) and PRISM (Figure 3B) indicate that HepG2 has a lower mRNA expression level of FTH1 compared to Hep3B cells, and the FTH1 expression level in HCC (the most common type of primary liver cancer) exhibited a significantly (Pearson correlation coefficient > 0.4) negative correlation with the sensitivity (the lower the AUC value, the higher the sensitivity) of the cells to erastin, a ferroptosis inducer [30]. The gene discussed is FTH1; the disease is liver cancer.