Thus, DYRK1A prevents epidermal growth factor receptor (EGFR) endocytosis-mediated degradation in neural stem cells [65] and indeed, DYRK1A-dependent EGFR stabilization has been described in glioblastoma (GBM) and non–small cell lung cancer (NSCLC) cell lines [66,67]. Here, EGFR is linked to lung cancer.