Our analysis of the TCGA data did not reveal any specific trend for DYRK3, which is under-expressed in breast (BRCA), kidney (KIHC), lung (LUAD and LUSC), prostate (PRAD) and thyroid (THCA) tumor cohorts and overexpressed in colon (COADREAD), HNSCC, kidney (KIRC) and stomach (STAD) cancer tissues (Table S1). Here, DYRK3 is linked to cancer.