CD274 and gastric cancer: Furthermore, two randomized phase II trials are currently ongoing: the DANTE trial (NCT 03421288) evaluating peri-operative use of atezolizumab (anti-PD-L1 antibody) combined with FLOT (docetaxel, oxaliplatin, leucovorin and 5-fluorouracil) [160] and the IMAGINE NCT04062656 randomized, four-arm, chemotherapy-controlled modular trial in subjects with histologically confirmed, resectable GC or GEJ adenocarcinoma.