WNT5A and chronic myelogenous leukemia, BCR-ABL1 positive: As a matter of fact, for CML, there is evidence that Wnt5a have β-catenin-dependent effects [105], whereas, in vivo, Wnt5a and DKK1 were described to act as proinflammatory agents and contribute to tumor suppression [78,108,109], hampering the understanding of Wnt5a in this context.