TNF and neoplasm: The HE staining and qPCR results indicated that DSF/Cu2+ resulted in necrotic areas of tumor tissues, and Abx could synergistically increase tumor necrosis areas to DSF/Cu2+, and the overexpression of pro‐inflammatory cytokines IL‐1β, IL‐6, and TNF‐α were observed in model group, while the combination of Abx and DSF/Cu2+ could reverse the level of inflammation (Figure 2).