LYPLA1 and diabetes mellitus: Our results suggest that diabetes does not interfere in the transcription of the cAMP responsive element binding protein 5, CREB5, in SMG, and LPLI did not change its mRNA levels expression, means of 1.20 ± 0.34, 2.44 ± 1.00 and 2.01 ± 0.79 for C0, D0 and D20, respectively (Fig 5A).