Previously in our lab, we demonstrated that (i) resveratrol possesses pro-apoptotic effects against human PCa cells without affecting the normal prostate epithelial cells, and (ii) the anti-proliferative effects of resveratrol against PCa cells may be mediated via modulation of phosphatidylinositol 3’-kinase (PI3K)/AKT pathway and BCL2 family of proteins [12]. Here, BCL2 is linked to posterior cortical atrophy.