Quercetin-3-O-glucoside can inhibit the expression of TNF-α, IL-1β and IL-6 and the activation of NF-κB, and simultaneously up-regulate the expression of Nrf-2 and HO-1, and inhibit the inflammation and oxidation to resist the induction of cisplatin of acute kidney injury in mice [61]. The gene discussed is TNF; the disease is acute kidney injury.