PHOX2B and neuroblastoma: Neuroblastoma tumors are mixed tumors, composed of an adrenergic component identified by the expression of Phox2b, Hand2, Gata3 and a mesenchymal component (also referred to as a NCC-like component) identified by the expression of Prrx1, Vim, Snai2, Fosl1/2, Jun and others [113, 114].