Study NCT03767582′s purpose is to evaluate if the combination of nivolumab and a CCR2/CCR5 dual antagonist (BMS-813160) with GVAX is safe in patients with locally advanced pancreatic cancer (LAPC) who have received chemotherapy and radiotherapy and to also evaluate if this combination therapy enhances the infiltration of CD8+CD137+ cells in PDAC. The gene discussed is CD8A; the disease is familial pancreatic carcinoma.