The current research demonstrated the correlation between PRKN and PACRG SNPs and serum lipid parameters including LDL-C (rs11966842 and rs2155510), TC (rs1105056, rs10755582, rs2155510, rs11966842 and rs6904305), and TG (rs9365344 and rs11966948) in subjects with hyperlipidaemia and TG (rs10755582 and rs11966948) in the normal group. The gene discussed is PACRG; the disease is hyperlipidemia.