MAPT and Alzheimer disease: Furthermore, the average length of mitochondria was decreased to 1.3 μm and 1.8 μm in AD model flies (GMR-GAL4-UAS-Mito-GFP/+; UAS-Aβ42E693G/+ and GMR-GAL4-UAS-Mito-GFP/+;UAS-APP.C99-UAS-MAPT/+), respectively, as compared to control flies (Fig. 6C,E and G).