APP and Alzheimer disease: The average length of mitochondria was significantly increased to 13.8 μm and 14.3 μm in Miro overexpressing AD model flies (GMR-GAL4-UAS-Mito-GFP/UAS-Miro; UAS-Aβ42E693G/+ and GMR-GAL4-UAS-Mito-GFP/ UAS-Miro;UAS-APP.C99-UAS-MAPT/+), respectively (Fig. 6D,F,G).