In the case of AD model flies (elav-Gal4C155/+;+/+;UAS-Aβ42E693G/+ and elav-Gal4C155/+;+/+;UAS-APP.C99-UAS-MAPT/+), the ATP was significantly decreased to 2.4×105 and 3.6×105 μM μg−1 of protein as compared to control flies (Fig. 7A). This evidence concerns the gene MAPT and Alzheimer disease.