APP and Alzheimer disease: Further, we observed the relative expression of ATP synthase beta was decreased to 0.4- and 0.5-fold in AD model flies such as elav-Gal4C155/+;+/+;UAS-Aβ42E693G/+ and elav-Gal4C155/+;+/+;UAS-APP.C99-UAS-MAPT/+, respectively, as compared to the control flies (Fig. 7B).