Knockdown of Miro in AD model flies genetic background [GMR-GAL4-UAS-TauWT/+;UAS-MiroRNAi/+,GMR-GAL4-UAS Aβ42(Human)/+;UAS-MiroRNAi/+, GMR-GAL4/+;UAS-ApplRNAi/UAS MiroRNAi] showed enhanced rough eye phenotype as well as ommatidial and bristles disarrangements (Fig. 2F–H,F′–H′). Here, LGALS4 is linked to Alzheimer disease.