While overexpression of Miro in an AD model fly genetic background (elav-Gal4C155/+; UAS-Miro/+;UAS-APP.C99-UAS-MAPT/+) increased the body weight to 12.39 mg, 11.15 mg and 10.59 mg, respectively (Fig. 2L). Here, APP is linked to Alzheimer disease.