Overexpression of Miro in AD model flies (elav-Gal4C155/+;UAS-Miro/+;UAS-Aβ42E693G/+ and elav-Gal4C155/+;UAS-Miro/+;UAS-APP.C99-UAS-MAPT/+) significantly decreased cell death (Fig. 8D,F,G) in the larval brain. This evidence concerns the gene APP and Alzheimer disease.