Comparisons of CGM to SMBG cited HbA1c reductions ranging from 0.23% (2.5 mmol/mol; from Garcia-Lorenzo et al.’s meta-analysis for their own economic evaluation) [33] to 0.6% (6.6 mmol/mol), citing the ‘Effect of continuous glucose monitoring on glycemic control in adults with type 1 diabetes using insulin injections: the DIAMOND randomized clinical trial’ (DIAMOND) study [47]. This evidence concerns the gene INS and type 1 diabetes mellitus.