ANGPTL8 and Abnormal renal physiology: Then, we further analysed the association of ANGPTL8 with any single component of the secondary outcomes and found that elevated ANGPTL8 was associated with an increased risk for renal dysfunction in the diabetic patients (RR in quartile 4 vs. quartile 1, 12.43; 95% CI 1.48–104.81; Table 3, model 3) after adjusting for covariables.