Moreover, ANGPTL8 levels positively correlated with age (r = 0.18), duration of diabetes (r = 0.08), 2 h PG (r = 0.08), alanine transaminase (ALT) (r = 0.07), AST (r = 0.13) and creatinine (r = 0.10) but inversely correlated with BMI (r = − 0.07), HDL (r = − 0.09) and eGFR (r = − 0.13) in diabetic patients (all p values < 0.05) (Additional file 1. This evidence concerns the gene GPT and diabetes mellitus.