ANGPTL8 and diabetes mellitus: However, the associations of ANGPTL8 with all-cause mortality only persisted in the diabetic patients, although they were slightly attenuated after additional adjustment for covariables, including age, sex and BMI (RR, 3.59; 95% CI 1.36–9.51; model 2) and further adjustment for lipid profiles and duration and treatment of diabetes (RR, 3.54; 95% CI 1.32–9.50; model 3).