Furthermore, levels of BMI, HbA1c, FPG, 2 h PG, fasting insulin, HOMA-IR, low density lipoprotein (LDL), TG, cholesterol, creatinine, and incident rates of hypertension and hyperlipidaemia in diabetic patients were higher than in the control subjects (all p < 0.05, Additional file 1. The gene discussed is INS; the disease is hypertensive disorder.