CD274 and non-small cell lung carcinoma: In addition, the NSCLC cells were treated with high-dose cisplatin (20 μg/ml), and the NSCLC cells pretreated with NSCLC cell derived exosomes were more resistant to cisplatin treatment, which could be abrogated by co-treating cells with anti-PD-L1 antibody (Fig. 5f-j).