Laboratory examination revealed hypoalbuminemia (serum albumin 1.0 g/dL), renal insufficiency (creatinine 0.61 mg/dL, creatinine-eGFR 43.7 mL/min/cm2, urea 28.2 mg/dL), hyperkalemia (potassium 6.7 mEq/L), anemia (Hb 9.6 g/dL, MCV 80.6 fL, MCH 25.8 pg, MCHC 31.9 g/dL), hyperlipidemia (triglycerides 709 mg/dL) and increased total cholesterol (total cholesterol 428 mg/dL). The gene discussed is ALB; the disease is anemia.