We found DMRs showing decreased methylation in MCI-AD converters relative to MCI-MCI nonconverters in the genes CPT1B and CHKB (932 bp; 14 probes) (Fig. 3A), TMEM184 A (659 bp; 6 probes) (Fig. 3B), KCNAB3 (558 bp; 7 probes) (Fig. 3C), GABBR1 (379 bp; 10 probes) (Fig. 3D), PRDM1 (121 bp; 5 probes) (Fig. 3E), FLJ37453 (568 bp; 6 probes) (Fig. 3F), and OR56A3 and TRIM5 (556 bp; 5 probes) (Fig. 3G). This evidence concerns the gene PRDM1 and Alzheimer disease.