Similarly, MUC4 is minimally expressed in PanIN and chronic pancreatitis but is highly expressed in PC cell lines,14, 27 and aberrant overexpression of MUC4 was also associated with the progression of PanIN to PC,28, 29 while the intensity of expression increased in parallel with the severity of cellular dysplasia.29 The gene discussed is MUC4; the disease is chronic pancreatitis.