Thus, the aim of this study was to verify whether single nucleotide polymorphisms(SNPs) in the ABCA1, ABCA7 andABCG1 genes influence variables related to obesity and lipidprofile in obese women and to evaluate the effect of these SNPs on anthropometricand lipid parameters in response to a weight-loss dietary intervention. Here, ABCA7 is linked to obesity due to melanocortin 4 receptor deficiency.