WIF1 and urinary bladder cancer: Silencing of the WIF1 gene due to promoterhyper-methylation has been revealed in gastrointestinal, lung and bladder cancers(Taniguchi et al., 2005;Urakami et al., 2006;Yoshino et al., 2009;Rahmani et al., 2017).It has also been observed that stimulation of WIF1 activity incancer cells allowed to treat some malignant cancers (Ng et al., 2014).