First, RA synoviocytes were transfected with si-ZFAS1#1+anti-miR-NC, si-ZFAS1#1+anti-miR-2682-5p, miR-2682-5p+pcDNA, miR-2682-5p+ADAMTS9, or pcDNA-ADAMTS9, respectively. This evidence concerns the gene ADAMTS9 and rheumatoid arthritis.