Our results suggested that SLC39A1, SLC39A3, SLC39A4, SLC39A5, SLC39A6, SLC39A7, SLC39A9, SLC39A10, SLC39A11 and SLC39A13 were significantly higher in cancer tissue than which in normal tissue, whereas, SLC39A8 and SLC39A14 expressed higher in normal tissue. This evidence concerns the gene SLC39A3 and cancer.