CXCL8 and keloid: This resulted in decreased expression of connective tissue growth factor (CTGF), interleukin-6 (IL-6), and interleukin-8 (IL-8), preventing keloid fibroblast migration and proliferation, as well as angiogenesis and collagen accumulation, which presented as the first step of favorable results by inhibiting keloid healing signaling pathways [30]​​​​​​.